Reappraisal of progestins in endometriosis therapy

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INVITED COMMENTARY Reappraisal of progestins in endometriosis therapy

Endocrine treatment of endometriosis is based upon the suggestion of Kistner that regression of endometriosis can be obtained by induction of pseudo-pregnancy with a combination of oestrogen and progestin (1). The 40-year history of conservative medical therapy of endometriosis demonstrates that many substances and their combinations have been tested, including low-dose oral contraceptives, pro...

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Progestins for symptomatic endometriosis: a critical analysis of the evidence.

OBJECTIVE To obtain estimates of the effects of progestin treatment for pelvic pain associated with endometriosis. DATA IDENTIFICATION Information from studies published in the English-language literature between 1966 and 1996 was pooled. Articles were identified through hand and computerized searches using MEDLINE. STUDY SELECTION A total of 27 trials that were published in peer-reviewed j...

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Progestin therapy in endometriosis.

Progestins are synthetic compounds that mimic the effects of progesteron. For over 50 years, oral progestins have been demonstrated to be effective in the treatment of endometriosis. They were reported to reduce or eliminate pain symptoms in approximately 90% of the patients. Progestins are available in many forms, including oral preparations, injections, subdermal implants and intrauterine sys...

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Progestins

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ژورنال

عنوان ژورنال: European Journal of Endocrinology

سال: 1998

ISSN: 0804-4643,1479-683X

DOI: 10.1530/eje.0.1380134